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BB20023: DNA (making, breaking & disease)

Academic Year: 2018/9
Owning Department/School: Department of Biology & Biochemistry
Credits: 6      [equivalent to 12 CATS credits]
Notional Study Hours: 120
Level: Intermediate (FHEQ level 5)
Period:
Semester 1
Assessment Summary: EX 60%, MC 20%, PR 20%
Assessment Detail:
  • Multiple Choice (MC 20%)
  • Practical (PR 20%)
  • Examination (EX 60%)
Supplementary Assessment:
Like-for-like reassessment (where allowed by programme regulations)
Requisites:
Description: Aims:
To provide an in-depth understanding of the relationship between DNA synthesis, damage & repair mechanisms in relation to cell cycle and apoptosis. Also provides an understanding of how disruption of normal cellular function leads to disease processes, especially cancer.

Learning Outcomes:
After taking this course the student should be able to:
* give a detailed account of DNA replication, damage and repair in prokaryotic and eukaryotic systems;
* describe and explain the cross talk between cell cycle and apoptosis in relation to oncogenesis;
* explain the rationale behind tumour therapy, either conventional approaches of radio/chemotherapy or newer approaches of genetherapy, immunotherapy, angiotherapy etc.

Skills:
Learning and studying T/F/A, Written communication T/F/A, Laboratory skills T/F, Information technology T/F, Information handling & retrieval T/F/A, Working independently T/F.

Content:
DNA replication and repair in relation to disease. Role of cell cycle and apoptosis in oncogenesis. Various modes of cancer therapy.
Programme availability:

BB20023 is Compulsory on the following programmes:

Department of Biology & Biochemistry
  • USBB-AFB02 : BSc(Hons) Biochemistry (Year 2)
  • USBB-AKB06 : BSc(Hons) Biochemistry with Professional Placement (Year 2)
  • UXXX-AFB11 : BSc(Hons) Biomedical Sciences (Year 2)
  • UXXX-AKB11 : BSc(Hons) Biomedical Sciences with Professional Placement (Year 2)
  • USBB-AFB05 : BSc(Hons) Molecular and Cellular Biology (Year 2)
  • USBB-AKB08 : BSc(Hons) Molecular and Cellular Biology with Professional Placement (Year 2)

BB20023 is Optional on the following programmes:

Department of Biology & Biochemistry

Notes:

  • This unit catalogue is applicable for the 2018/19 academic year only. Students continuing their studies into 2019/20 and beyond should not assume that this unit will be available in future years in the format displayed here for 2018/19.
  • Programmes and units are subject to change in accordance with normal University procedures.
  • Availability of units will be subject to constraints such as staff availability, minimum and maximum group sizes, and timetabling factors as well as a student's ability to meet any pre-requisite rules.
  • Undergraduates: .
  • Postgraduates: .